Atypical type A thymoma component identified by pulmonary metastasectomy 11 years after surgery of type AB thymoma

Atypical type A thymoma component identified by pulmonary metastasectomy 11 years after surgery of type AB thymoma

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Atypical type A thymomas exhibit more aggressive features than conventional type A thymomas.Type AB thymomas rarely have atypical type A components.We report a rare case of type AB thymoma with an atypical type A component, that was identified after pulmonary metastasectomy 11 years after the primary surgery and long-term follow-up after recurrence.A 61-year-old female 03.2150.400 underwent extended thymectomy for an anterior mediastinal tumor 11 years prior and was diagnosed with type AB thymoma (Masaoka stage II).Five years ago, follow-up computed tomography showed well-circumscribed pulmonary nodules up to 1.

0 cm in both lungs.All the pulmonary nodules grew slowly; however, one of the nodules grew to 1.6 cm, and thoracoscopic wedge resection was performed for diagnosis.Pathologically, the pulmonary nodule was consisted of type A thymoma component.Conventional type AB thymomas are usually locally aggressive neoplasms; thus, we reviewed the tissue slides medline guardian toilet safety rails of primary thymomas.

Histologically, cytological atypia, hypercellularity, and increased mitosis are observed in the type A component.Consequently, the diagnosis was revised to a type AB thymoma with an atypical type A component.The pulmonary nodule exhibited the same atypical type A features.Pulmonary metastasectomy was performed two more times as volume-reduction surgery.The residual metastasis was located only in the lung with slow growth, 4 years after the first pulmonary resection; therefore, we followed up as an outpatient without treatment.